Triquilar ED is a combined oral contraceptive (often called “the Pill”) consisting of 21 small hormonal tablets which contain a small amount of two different female hormones. These are levonorgestrel (a progestogen) and ethinyloestradiol (an oestrogen). Because of the small amount of hormones, Triquilar ED is considered a low-dose combined oral contraceptive preparation. The Triquilar ED blister pack contains 3 different kinds of active tablets, each kind featuring different amounts of two hormones. The sequencing of these tablets is intended to emulate a woman’s natural hormonal cycle by generating three distinct hormonal stages. This is why Triquilar ED is called a triphasic combined oral contraceptive. Triquilar ED also contains 7 large white non-hormonal tablets that do not contain any active ingredients.
Indications: oral contraceptive
Side effects: emotional lability (mood swings), depression and depressive mood, migraine, nausea, breast pain, unscheduled uterine bleeding (bleeding between periods), genital tract bleeding (vaginal bleeding). Less common is decrease and loss of libido (reduced or loss of sexual drive). Rare side effects are venouse and arterial thromboembolic events. If you notice any side effects not mentioned, please inform your doctor.
Contraindications: do not take Triquilar ED if:
- you have, or have ever had a disorder affecting the blood circulation, in particular those conditions relating to thrombosis. Thrombosis is the formation of a blood clot. This may occur in the blood vessels of the legs (deep vein thrombosis), the lungs (pulmonary embolism), the heart (heart attack), the brain (stroke), or other parts of the body.
- you have or have ever had a stroke (caused by a rupture of a blood vessel in the brain or a blood clot).
- you have or have ever had a condition that may be a first sign of a heart attack (such as angina pectoris or chest pain) or stroke (such as transient ischemic attack or small reversible stroke).
- you have diabetes mellitus with blood vessel damage.
- you have or have had pancreatitis (an inflammation of the pancreas) associated with high levels of fatty substances in your blood.
- you or someone in your immediate family have or have had high blood levels of cholesterol or triglycerides (fatty substances).
- you have or have had jaundice (yellowing of the skin) or severe liver disease as long as liver function values have not returned to normal.
- you have or have had a cancer that may grow under the influence of sex hormones (e.g. of the breast or the genital organs).
- you have or have had a benign or malignant liver tumor.
- you have a history of migraine accompanied by visual symptoms or speech disability or weakness or numbness in any part of your body.
- you have any unexplained vaginal bleeding.
- you are pregnant or think you might be pregnant.
- you are hypersensitive (allergic) to any of the ingredients of Triquilar ED.
If any of these conditions appear for the first time while using Triquilar ED, stop taking it at once and consult your doctor. In the meantime, use non-hormonal contraceptive measures.
Important information: you may need to be kept under close observation of doctor if:
- you smoke
- you have diabetes
- you are overweight
- you suffer from migraine or headaches
- you suffer from epilepsy
- you have high blood pressure
- you have a heart valve disorder or a certain heart rhythm disorder
- you have an inflammation of your veins (superficial phlebitis)
- you have varicose veins
- anyone in your immediate family has had thrombosis, a heart attack or a stroke
- anyone in your immediate family has had breast cancer
- you have liver, kidney or gallbladder disease
- you have Crohn’s disease or ulcerative colitis (chronic inflammatory bowel disease)
- you have systemic lupus erythematosus (SLE; a disease affecting the skin all over the body)
- you have haemolytic uraemic syndrome (HUS; a disorder of blood clotting causing failure of the kidneys)
- you have sickle cell disease
- you have a condition that occurred for the first time or worsened during pregnancy or previous use of sex hormones (e.g. hearing loss, a metabolic disease called porphyria, a skin disease called herpes gestationis, a neurological disease called Sydenham’s chorea);
- you have or have had chloasma (yellowish-brown pigmentation patches on the skin, particularly of the face); if so, avoid exposure to the sun or ultraviolet radiation
- you have hereditary angioedema; exogenous oestrogens may induce or exacerbate symptoms of angioedema. You should see your doctor immediately if you experience symptoms of angioedema such as swollen face, tongue and/or pharynx and/or difficulty swallowing or hives together with difficulty breathing.
If any of above conditions appear for the first time, come back or get worse while using the Triquilar ED, you should contact your doctor.
Use and dosage: take your tablet at about the same time each day, with some water. Follow the direction of the arrows until all the tablets have been taken. A period (the withdrawal bleed) should begin during the 7 days of taking the larger white non-hormonal tablets. Start taking your next pack on the very next day after you have completed your last pack. This means that you will always start new packs on the same day of the week, and also that you will have your withdrawal bleed on about the same day each month.
Missed dose: if you forget to take your tablets, follow the instructions below. This is often called the “7 day rule”. The more tablets you have missed, the higher the risk that the contraceptive effect is decreased. There is a particularly high risk of becoming pregnant if you miss tablets at the beginning or at the end of the pack.
- If you have forgotten to take one or more of the large white non-hormonal tablets – there is no need to be concerned, simply take your next tablet, the next day as usual. However to make sure that you do not change your Pill taking rhythm, which is important for the contraceptive reliability of your Pill, you should proceed with your next tablet the next day at the normal time and discard the forgotten non-hormonal tablet(s) to avoid any confusion.
- If you are less than 12 hours late in taking one of the small hormonal Triquilar ED tablets, you are still protected against pregnancy. Take the tablet as soon as you remember and take the next one at your usual time. This may mean that you are taking 2 tablets in one day.
- If you are more than 12 hours late in taking one of your small hormonal Triquilar ED tablets, you will not be protected. Take the last tablet as soon as you remember and take the next one at your normal time. This may mean taking 2 tablets in one day. You must take extra contraceptive precautions and you must follow the 7 day rule. Read the section on “Extra contraceptive precautions” and “The 7 day rule” carefully.
- If you forget tablets in the first week after taking the large non-hormonal tablets and had intercourse in the seven days before, consult your doctor as the possibility of pregnancy should be considered.
- If you have forgotten to take your small hormonal Triquilar ED tablets for a few days, consult your doctor to be sure you are not pregnant, then discard the missed tablets and follow the 7 day rule.
Package Contents: each box of Triquilar ED contains 1 blister of Triquilar ED with 28 tablets containing female hormons specified as Active ingredient below.
Active ingredient: levonorgestrel 50 mcg and ethinyloestradiol 30 mcg – 6 light-brown tablets, levonorgestrel 75 mcg and ethinyloestradiol 40 mcg – 5 small white tablets, levonorgestrel 125 mcg and ethinyloestradiol 30 mcg – 10 ochre tablets, hormone-free lactose monohydrate – 7 large white tablets.
Manufacturer: Bayer Weimar GmbH und Co. KG, Weimar, Germany
Storage: keep Triquilar ED in its calender blister until used. Store at room temperature below 30°C, keep away from direct sunlight and do not refrigerate.